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Do not use this medication if you have ever had a serious allergic reaction to ZyloprimStop taking the medicine and call your doctor at once if you have any signs of skin rashno matter how mild.

Hyperuricemia may be primaryas in goutor secondary to diseases such as acute and chronic leukemiapolycythemia veramultiple myelomaand psoriasisIt may occur with the use of diuretic agentsduring renal dialysisin the presence of renal damageduring starvation or reducing dietsand in the treatment of neoplastic disease where rapid resolution of tissue masses may occurAsymptomatic hyperuricemia is not an indication for treatment with Zyloprimsee INDICATIONS AND USAGE

Tolbutamide’s conversion to inactive metabolites has been shown to be catalyzed by xanthine oxidase from rat liverThe clinical significanceif anyof these observations is unknown.

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